Melittin, a honeybee venom derived peptide for the treatment of chemotherapy-induced peripheral neuropathy

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Melittin, a honeybee venom-derived antimicrobial peptide, may target methicillin-resistant Staphylococcus aureus

Methicillin‑resistant Staphylococcus aureus (MRSA) is difficult to treat using available antibiotic agents. Honeybee venom has been widely used as an oriental treatment for several inflammatory diseases and bacterial infections. The venom contains predominantly biologically active compounds, however, the therapeutic effects of such materials when used to treat MRSA infections have not been inve...

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Chemotherapy-induced peripheral neuropathy.

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Chemotherapy-induced peripheral neuropathy

Neuropathy is associated with side effects of frontline chemotherapeutics, which is a prominent therapy utilized in prevalent cancers. Peripheral neuropathy negatively impacts quality of life in cancer patients and survivors. It also affects the dose plan of the treatment, thereby limiting the efficacy of the treatment. We searched the electronic database PubMed for pre-clinically and clinicall...

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ژورنال

عنوان ژورنال: Medical Oncology

سال: 2021

ISSN: 1357-0560,1559-131X

DOI: 10.1007/s12032-021-01496-9